Scientific Program

  • [Day 0] October 29 (Wed)
  • [Day 1] October 30 (Thu)
  • [Day 2] October 31 (Fri)
  • [Day 3] November 1 (Sat)

*Co-host

[Day 0] October 29 (Wed)
Time(KST)
Room B (Premier Ballroom A+B)
16:30-18:00 Spotlight on Excellence: Active Members of KAI 2025
Korean Session
Chair Jin-young Choi (The Catholic University of Korea, KOR)>
Il-Kyu Choi (DGIST, KOR)
16:30-16:50
From Inflammatory Imprints to Immune Reprogramming: Targeting Microglial Dysregulation and Amyloid Pathology in Alzheimer’s Disease
Hyungseok Seo
(Seoul National University, KOR)
16:50-17:10
Epithelial Coordination of Immune-Microbe-Nutrient Interactions in the Gut
Ye-Ji Bang
(Seoul National University, KOR)
17:10-17:30
Heterogeneity and Functional Capacity of VZV-Specific Memory CD4 T Cells Across Aging
Chulwoo Kim
(Korea University, KOR)
17:30-17:50
Understanding Cellular Cross-Talk in Pathogenic Type 17 Immunity in Psoriatic Skin through Single-Cell Multi-Omics analysis
Seunghee Hong
(Yonsei University, KOR)
17:50-18:00
Discussion
[Day 1] October 30 (Thu)
Time(KST)
Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
8:30 Registration
09:40-09:50 Presidential Address
09:50-10:40 Plenary Lecture 1
Chair Jeehee Youn (Hanyang University, KOR)
How Autoantibody-Producing Cells Develop and Survive in Autoimmune Diseases and After CAR-T Cell Therapy
Carola Vinuesa
(The Francis Crick Institute, GBR)
10:40-11:00 Coffee Break
11:00-12:40 Symposium 1 - Tissue-Specific Immunity
[Yonsei ‘Eokkaedongmu Project (어깨동무사업)’]*
Symposium 2 - KAI-AKIA
[Korea US Collaborative Research Fund - Korea BioDefense Research Institute]*
KAI Basic & Clinical Joint Academic Awardee Lecture
Korean Session
Chair Jongsoon Lee(Soonchunhyang University, KOR)
Ye-Ji Bang(Seoul National University, KOR)
Chair Lark-Kyun Kim(Yonsei University, KOR)
Seung-Ki Kwok(The Catholic University of Korea, KOR)
Chair Seokmann Hong(Sejong University, KOR)
11:00-11:25
Inflammatory hematopoiesis contributes to intestinal inflammation and is modulated by common therapy
11:00-11:25
CD3⁺ CD4⁻ CD8⁻ double negative T cell as platform for off-the-shelf CAR-T cell therapy
11:00-11:10
Award Ceremony
11:10-11:40
KAI Basic & Clinical Joint Academic Awardee Lecture: Organ Crosstalk in Inflammatory diseases: Microbiota and Gene Bridging Gut, Liver, and Joints
Rachel Niec
(Memorial Sloan Kettering Cancer Center, USA)
Jongbok Lee
(University of Calgary, CAN)
Donghyun Kim
(Seoul National University, KOR)
11:25-11:50
Investigating the functional heterogeneity of hepatic macrophages
11:25-11:50
CRY1 fuels resistance to immunotherapy in NANOGhigh tumors
11:40-11:50
Q&A
Charlotte Louise Scott
(VIB and the Universities of Ghent, BEL)
Tae Woo Kim
(Korea University, KOR)
Meet the Editor
ChairIl-Kyu Choi (DGIST, KOR)
11:50-12:15
mGluR5 function of liver resident Kupffer cells in alcohol-associated steatohepatitis
11:50-12:15
Host-Directed Therapy for Respiratory Viral Infection
11:50-12:15
An Inside Look at Publishing in Science Immunology
Won-Il Jeong
(KAIST, KOR)
Seungmin (Sam) Hwang
(Broad Institute of MIT and Harvard, USA)
Christiana Fogg
(Science Immunology Editor)
12:15-12:40
Regulation of blood-brain barrier integrity and neuroinflammation
12:15-12:40
KAI-Seegene Medical Foundation Excellence Award Lecture: Single-Cell Dissection of Human Immune Diversity: Pathogenic Skewing in Autoimmune Diseases
12:15-12:40
How to publish in Nature Communications
Je-Wook Yu
(Yonsei University, KOR)
Jeong Seok Lee
(KAIST, KOR)
Ching-yu Huang
(Nature Communications Editor/Immunology Team Chief Editor)
12:40-13:30 Luncheon Symposium 1 AbbVie Luncheon Symposium 2 Eisai Korea Luncheon Symposium 3 Celltrion
Chair Seung Cheol Shim(Chungnam National University, KOR) ChairEun Young Lee(Seoul National University, KOR) ChairSeung-Ki Kwok (The Chatholic Universirt of Korea, KOR)
12:40-13:30
Expanding Role of JAK inhibitor in the Management of axSpA
12:40-13:30
The difference among JAK-inhibitors : From basic science to clinical trial
12:40-13:30
Role of IL-6 and Efficacy of CT-P47 (Avtozma, tocilizumab biosimilar)
Hong-Ki Min
(Konkuk University, KOR)
Su-Jin Moon
(The Catholic University of Korea, KOR)
Seokchan Hong
(University of Ulsan, KOR)
13:30-14:30 Poster Session
14:30-14:50 Coffee Break
14:50-16:30 Symposium 3 - Immunometabolism
[Innate Immune-Mediated Chronic Inflammatory Disease Medical Research Center]*
Symposium 4 - DC & Myeloid cells
[Biospecimen-Multiomics Digital Bioanalysis Core Facility]*
Symposium 5 - Cancer Immunology
[Personalized Cancer Immunotherapy Research Center] *
Chair Chung-Gyu Park(Seoul National University, KOR)
Jin Young Huh(Sogang University, KOR)
Chair Young-Min Hyun(Yonsei University, KOR)
Seungjin Ryu(Chung-Ang University, KOR)
Chair Jun Young Hong(Yonsei University, KOR)
Tae Jin Kim(Sungkyunkwan University, KOR)
14:50-15:15
Decoding the Immunological Lipidome
14:50-15:15
Tissue Macrophage Heterogeneity
14:50-15:15
Epigenetic Regulation of Tumor Immunity
Autumn G. York
(University of Washington, USA)
Florent Ginhoux
(Gustave Roussy, FRA)
Diana Clare Hargreaves
(Salk Institute, USA)
15:15-15:40
Mitochondria-mediated guidance in tailoring T cell anti-tumor immunity and beyond
15:15-15:40
The immune system and its role in adaptive physiology
15:15-15:40
Probing Key Immune Feedback Modulators for Immunotherapy of Cancer and Beyond
Ping-Chih Ho
(University of Lausanne, CHE)
Andrew Wang
(Yale University, USA)
Jun Wang
(New York University, USA)
15:40-16:05
The impact of viral infections on systemic immunometabolism and viral control
15:40-16:05
CTCF shapes the 3D enhancer network in dendritic cells
15:40-16:05
Tox-mediated immune regulation of regulatory T cells during cancer progression
Bojan Polić
(University of Rijeka, HRV)
Hyoung-Pyo Kim
(Yonsei University, KOR)
Sang-Jun Ha
(Yonsei University, KOR)
16:05-16:30
Lipid metabolic control of plasma cell
16:05-16:30
Emerging pathogenic myeloid cell populations in diseases
16:05-16:30
Engineering next generation T cell therapy for Cancer
Yeonseok Chung
(Seoul National University, KOR)
Yoe-Sik Bae
(Sungkyunkwan University, KOR)
Chan Hyuk Kim
(Seoul National University, KOR)
16:30-16:50 Coffee Break
16:50-17:40 Plenary Lecture 2
Chair Sin-Hyeog Im (POSTECH & ImmunoBiome, KOR)
16:50-17:40
The role of Kruppel-like factors in T cell trafficking and differentiation
Stephen Jameson
(University of Minnesota, USA)
[Day 2] October 31 (Fri)
Time (KST) Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
09:00-10:40 Symposium 6 - Multi-omics in Immunology Symposium 7 - Immune Aging Symposium 8 - B cell & Humoral Immunity
Chair Murim Choi(Seoul National University, KOR)
Jinwook Choi(GIST,KOR)
Chair Eui-Cheol Shin(KAIST, KOR)
Seung-Woo Lee(POSTECH, KOR)
Chair Jong-Seok Lim(Sookmyung women's university, KOR)
Ji Eun Oh(KAIST, KOR)
09:00-09:25
Regulation of intestinal tolerance by Thetis cells
09:00-09:25
Genomic signatures of human immune aging and reduced vaccine responses
09:00-09:25
Effector and tissue-residing memory B cells - First Responders in health and disease
Chrysothemis Brown
(Memorial Sloan Kettering Cancer Center, USA)
Duygu Ucar
(The Jackson Laboratory for Genomic Medicine, USA)
Frances Lund
(University of Alabama at Birmingham, USA)
09:25-09:50
Inflammation-induced epigenetic and functional reprogramming of HSC and myeloid cells
09:25-09:50
IL-15-induced NK-like activation of senescent CD8+ T cells
09:25-09:50
Type 1 follicular helper T cells are required for long-lived IgA plasma cell development following mucosal viral infection
Steven Josefowicz
(Weill Cornell Medicine, USA)
Eui-Cheol Shin
(KAIST, USA)
Jennifer Gommerman
(University of Toronto, CAN)
09:50-10:15
Lifetime dynamics of immune cells and the immune repertoire revealed by integrative single-cell analysis
09:50-10:15
Peroxisomes and Macrophage Senescence
09:50-10:15
Strategies to maximize vaccination efficacy and antigen-specific immune responses 
Jong Eun Park
(KAIST, KOR)
Jie Sun
(The University of Virginia, USA)
Cheol-Heui Yun
(Seoul National University, KOR)
10:15-10:40
Immuno-genomic interactions in lung cancer
10:15-10:40
Heterogeneity and Functional Profiling of Human Monocytes During Aging
10:15-10:40
Leukocyte-Specific Protein-1 (LSP-1) Regulation of B Cell Autoimmunity
Hae-Ock Lee
(The Catholic University of Korea, KOR)
Won-Woo Lee
(Seoul National University, KOR)
Wan-Uk Kim
(The Catholic University of Korea, KOR)
10:40-11:00 Coffee Break
11:00-12:40 Symposium 9 - T cell Biology Symposium 10 - Mucosal Immunity & Microbiota Symposium 11 - Infection & Immunity[VITAL-Korea]*
Chair Chang-Duk Jun(GIST,KOR)
Wan-Uk Kim(The Catholic University of Korea, KOR)
Chair Yeonseok Chung(Seoul National University, KOR)
Donghyun Kim(Seoul National University, KOR)
Chair Jeon-Soo Shin(Yonsei University, KOR)
Chulwoo Kim(Korea University, KOR)
11:00-11:25
Epigenetic Mechanisms of T cell Exhaustion Limiting Tumor Immunotherapy
11:00-11:25
Functional diversification of diet by the human gut microbiome
11:00-11:25
Human virus-specific CD8+ T cell zonation at single-lymph-node resolution.
Benjamin Youngblood
(St. Jude Children’s Research Hospital, USA)
Seth Rakoff-Nahoum
(Harvard Medical School, USA)
Marcus Buggert
(KarolinskaInstitutet, SWE)
11:25-11:50
The diverse roles of TGF-beta signaling in controlling T cell functions
11:25-11:50
Neuronal Regulation of Intestinal Immune Homeostasis and Inflammation
11:25-11:50
Inflammation as a Driver of Mycobacterium tuberculosis pathogenesis
Yisong Wan
(University of North Carolina at Chapel Hill, USA)
Heping Xu
(Westlake University, CHN)
Christina L. Stallings
(Washington University, USA)
11:50-12:15
Role of ETV5 in Tfh cell differentiation and lupus pathogenesis
11:50-12:15
Skin microbiome-driven immune imprinting in early life
11:50-12:15
Toxoplasma gondii-derived Peptides as Dual-Function Agents to Overcome Drug Resistance in Infection and Cancer
Yoontae Lee
(POSTECH, KOR)
Ji-Hwan Ryu
(Yonsei University, KOR)
Chul-Su Yang
(Hanyang University, KOR)
12:15-12:40
A novel molecular mechanism of T cell exhaustion in anti-tumor immunity
12:15-12:40
Macrophage in Asthma: who are they?
12:15-12:40
Senescence of endothelial cells increases susceptibility to KSHV infection via CD109-mediated viral entry
Kyungho Choi
(Seoul National University, KOR)
Hye-Ryun Kang
(Seoul National University, KOR)
Myung-Shin Lee
(Eulji University, KOR)
12:40-13:30 Luncheon Symposium 4 Acrobiosystems Luncheon Symposium 5 Novartis Korea Luncheon Symposium 6 BD Korea
Chair Chair Su-Jin Moon (The Chatholic Universirt of Korea, KOR) Chair Sang-Jun Ha (Yonsei University, KOR)
12:40-13:30
Exploring Popular Target Proteins in Autoimmune Diseases Design, Development, and Applications
12:40-13:30
Unveiling the Role of IL-17 in SpA Pathogenesis
12:40-13:00
CellView and SpectralFX technology: Distinct Paths for Deep Science
WenLin Ren
(ACROBiosystems)
Yeonseok Chung
(Seoul National University, KOR)
Robert S. Balderas
(BD Global Vice President, USA)
13:30-14:30 Poster Session
14:30-14:50 Coffee Break
14:50-16:30 Symposium 12 - Neuro-Immune Crosstalk
[Tissue-Sensory-Immune Axis Global Science Research Center]*
Symposium 13 - Innate Lymphocytes Symposium 14 - Cancer Immunotherapy
(Clinical Session)
Chair Je-Min Choi(Hanyang University, KOR)
Ho Jin Kim(National Cancer Center, KOR)
Chair Yong-Suk Jang(Jeonbuk National University, KOR)
Hye Young Kim(Seoul National University, KOR)
Chair Soo Seok Hwang(Seoul National University, KOR)
Hyungseok Seo(Seoul National University, KOR)
14:50-15:15
Neuronal control of cutaneous inflammation
14:50-15:15
The role of ILC2 in tissue homeostasis and neoplasia
14:50-15:15
Allogeneic iPSC-derived iNKT cells in recurrent head and neck cancer: A Phase 1 Trial
Dan Kaplan
(University of Pittsburgh, USA)
Timotheus You Fu Halim
(University of Cambridge, GBR)
Shinichiro Motohashi
(Chiba University, JPN)
15:15-15:40
The role of innate immunity in CNS inflammation
15:15-15:40
Functional Plasticity of ILCs in Asthma
15:15-15:40
CD7 CAR-T Therapy: opportunities, challenges and innovations
Andrew Mendiola
(University of California San Diego, USA)
Hye Young Kim
(Seoul National University, KOR)
Peihua Lu
(Lu Daopei Hospital, CHN)
15:40-16:05
Neuro-glial interactions in neurodegeneration
15:40-16:05
HPK1 dysregulation-associated NK cell dysfunction promotes metastatic tumor progression
15:40-16:05
Development of CAR-T therapy
Won-Suk Chung
(KAIST/IBS, KOR)
Hun Sik Kim
(University of Ulsan, KOR)
Hyoung Jin Kang
(Seoul National University, KOR)
16:05-16:30
The therapeutic potential of natural killer cells in neuropathic pain
16:05-16:30
Development of innate T cells in mice and humans
16:05-16:30
Current Progress in CAR T-Cell Therapy for B-Cell Lymphoma.
Seog Bae Oh
(Seoul National University, KOR)
You Jeong Lee
(Seoul National University, KOR)
Dok Hyun Yoon
(University of Ulsan, KOR)
16:30-16:50 Coffee Break
16:50-17:40 Plenary Lecture 3
Chair Moon Jung Song (Korea University, KOR)
16:50-17:40
Mechanisms linking tissue inflammation to fibrosis
Ramnik Xavier
(Broad Institute and Harvard Medical School, USA)
[Day 3] November 1 (Sat)
Time (KST) Room A (Grand Ballroom A+B) Room B (Premier Ballroom A+B) Room C (Grand Ballroom C)
09:00-10:40 Young Investigator Symposium
[WBR Award and YIP Award] *
Joint Session 1
*[Korean College of Rheumatology/대한류마티스학회]
Korean Session
Joint Session 2
*[The Korean Academy of Asthma, Allergy and Clinical Immunology/대한천식알레르기학회]
Korean Session
ChairJune-Yong Lee (Yonsei University, KOR)
Min Kyung Jun(Institute for Basic Science, KOR)
Chair Hong-Ki Min(Konkuk University, KOR)
Jungsik Song(Yonsei University, KOR)
Chair Yae-Jean Kim(Sungkyunkwan University, KOR)
Sae-Hoon Kim(Seoul National University, KOR)
09:00-09:15
[OP-001] Acquisition of Immunoregulatory Functions by Notch2-Expressing Phenotypically Exhausted CD4⁺ T Cells
09:00-09:25
Lupus nephritis
09:00-09:25
Tissue crosstalk mediated by ILC2s in chronic inflammation
So-Eun Bae
(Seoul National University, KOR)
Seokchan Hong
(University of Ulsan, KOR)
Seungwon Ryu
(Gachon University, KOR)
09:15-09:30
[OP-002] Human CD127⁺CD45RA⁺CD8⁺ T cells that have lost CCR7 expression represent memory precursor effector cells governed by FOXP1
09:25-09:50
Gout & inflammasome
09:25-09:50
Mechanical stretch mediated type 2 immune circuits in mucosal tissues
So-Young Kim
(KAIST, KOR)
Jooha Lee
(The Catholic University of Korea, KOR)
Do-Hyun Kim
(Hanyang University, KOR)
09:30-09:45
[OP-003] Th1-Poised Naive CD4 T Cells as indicators of Anti-Tumor Immunity and Inflammatory Responses
09:50-10:15
Sjogren syndrome treatment unmet need
09:50-10:15
Discovery of Biomarkers based on Multi-Omics analysis in Asthma
Jae-Won Yoon
(Hanyang University, KOR)
Su-Jin Moon
(The Catholic University of Korea, KOR)
Tae-Bum Kim
(University of Ulsan, KOR)
09:45-10:00
[OP-004] PD-1 restricts lipid-driven cytotoxic reprogramming of ILC2s to limit innate anti-tumor immunity
10:15-10:40
Axial spondyloarthritis new bone formation
10:15-10:40
Pediatric food-related clinical allergy: a practical approach to various spectrum of diseases
Jongho Ham
(Seoul National University, KOR)
Sungsin Jo
(Soonchunhyang University, KOR)
Dong In Suh
(Seoul National University, KOR)
10:00-10:15
[OP-005] Redirecting cytotoxic lymphocytes to breast cancer tumors via metabolite-sensing receptors
Young-Min Kim
(Stanford University, USA)
10:15-10:30
[OP-006] Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre-existing immunity in mice
Dong-Il Kwon
(Yale University, USA)
10:40-11:00 Coffee Break
11:00-12:40 Symposium 15 - Autoimmune Disease Symposium 16 - Inborn Errors of Immunity (Clinical Session) Joint Session 3 *[Korean Association for the Study of Intestinal Diseases/대한장연구학회]
Chair Kyung-Mi Lee(Korea University, KOR)
Yong Woo Jung(Korea University, KOR)
Chair Dae Chul Jeong(The Catholic University of Korea, KOR)
Kangmo Ahn(Sungkyunkwan University, KOR)
Chair Sung-Gyoo Park(Seoul National University, KOR)
Seong-Joon Koh (Seoul National University, KOR)
11:00-11:25
Immunology of interstitial lung disease, regulation of profibrotic macrophages
11:00-11:25
Primary Atopic Disorders
11:00-11:25
Insights from Fecal Microbiota Transplantation: Advancing Our Understanding of Host-Microbiome Interactions
Robert Lafyatis
(University of Pittsburgh, USA)
Lau Yu Lung
(University of Hong Kong, CHN)
Kwang Woo Kim
(Seoul National University, KOR)
11:25-11:50
T cell metabolism in autoimmune diseases
11:25-11:50
Inborn Errors of Immunity – informing us on common atopic disease
11:25-11:50
Crosstalk between the Gut Microbiome and Mucosal Immunity under Dietary Shifts
Michihito Kono
(Hokkaido University, JPN)
Cindy S Ma
(Garvan Institute of Medical Research, AUS)
Joo-Hong Park
(Seoul National University, KOR)
11:50-12:15
Genomic and transcriptomic Biomarkers for Clinical Applications in Rheumatology
11:50-12:15
JAK inhibitors treatment in Inborn Errors of Immunity
11:50-12:15
Tissue-resident T cell characterization in Crohn's disease
So Young Bang
(Hanyang University, KOR)
Yae-Jean Kim
(Samsung Medical Center, KOR)
Ho-Su Lee
(University of Ulsan, KOR)
12:15-12:40
Self double-stranded RNAs as drivers of aberrant immune activation
12:15-12:40
Autoinflammatory Diseases: Mechanisms and Treatment of Pyrinopathies
12:15-12:40
Programmable probiotics for personalized cancer immunotherapy
Yoosik Kim
(KAIST, KOR)
Wonyong Lee
(Institute for Basic Science (IBS), KOR)
Nicholas Arpaia
(Columbia University, USA)
12:40-13:20Short talk Session 1
(Luncheon)
Short talk Session 2
(Luncheon)
Short talk Session 3
(Luncheon)
Chair Jinwook Choi(GIST, KOR) Chair Ji Eun Oh(KAIST, KOR) Chair Jun Young Hong(Yonsei University, KOR)
12:40-12:50
[ST-001] The eosinophil-neutrophil interactions during allergic airway inflammation are regulated by GPR43 signaling
12:40-12:50
[ST-005] Acute Neuroinflammation Induces Prolonged Transcriptional and Functional Reprogramming in Microglia
12:40-12:50
[ST-009] Liver PD-1+ TREG cells with tissue-homing features are highly suppressive resembling tumor-infiltrating TREG cells
Jihyun YU
(KAIST, KOR)
Sehoon Moon
(Seoul National University, KOR)
Bae-Hyeon Moon
(KAIST, KOR)
12:50-13:00
[ST-002] Transient silencing of hypermutation preserves B cell affinity during clonal bursting
12:50-13:00
[ST-006] GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging
12:50-13:00
[ST-010] Mitochondrial Calcium Overload Drives CD8⁺ T Cell Senescence
Juhee PAE
(The Rockefeller University, USA)
In Hwa JANG
(University of Minnesota, USA)
Daehong KIM
(Seoul National University, KOR)
13:00-13:10
[ST-003] Kupffer cell-mediated intrahepatic T cell priming diversifies T cell differentiation and boost anti-tumor immunity in hepatocellular carcinomas
13:00-13:10
[ST-007] Voltage-gated T-type calcium channel blockers reduce apoptotic body-mediated SARS-CoV-2 cell- to- cell spread and subsequent cytokine storm
13:00-13:10
[ST-012] Human intestinal M cells act as dendritic cell–like antigen-presenting cells for gluten antigen via MHC II
Jaeoh PARK
(University of Lausanne, CHE)
Thanh Kha Phan
(La Trobe University, AUS)
Sangho Lim
(Hubrecht Institute, Royal Netherlands Academy of Arts and Science (KNAW) and UMC Utrecht Oncode Institute, NLD)
13:10-13:20
[ST-004] Exhaustion-driven ETV4 activation breaks the formation of functionally superior CD74+ exhausted CD8+ T cells
13:10-13:20
[ST-008] Gut Microbial Butyrate Promotes T Follicular Helper Cell Function and Vaccine Efficacy
Dongwook LEE
(POSTECH, KOR)
Haeun KO
(POSTECH, KOR)
13:20-13:30 Break
13:30-13:50 KAI Grand Achievement Award &
KAI-Seegene Medical Foundation Excellence Award Ceremony
13:50-14:40 Plenary Lecture 4
Chair Gap Ryol Lee(Sogang University, KOR)
13:50-14:40
KAI Grand Achievement Award Lecture - From Lymph Nodes to the Brain: B Cells as Gatekeepers of Checkpoint Immunotherapy
Heung Kyu Lee
(KAIST, KOR)
14:40-15:00 Awards & Closing Ceremony (Room A)